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     A pandemic refers to a disease that is existing in almost all parts of the world. It is awidespread outbreak of an infectious disease   36   place across international boundaries andaffecting lots of people. It can also happen in agricultural animals and plants such as cattle andbananas. There   37   some major pandemics recorded in human history,   38   , cholera,smallpox, tuberculosis, and influenza. One of the most serious pandemics was the Black Deathwhich killed nearly half the people of western Europe in the 14th century.   39   fight againstpandemics, the World Health Organization (WHO) has come up with a flow chart that showshow a new virus moves from the first few infections in human beings to a pandemic. Thisbegins with the virus infecting animals. Then the virus moves to the   40   where it spreadsamong people. Finally, the pandemic ends when infections have spread internationally and areeffectively controlled afterwards.

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